A BUILT-IN CPG ADJUVANT IN RSV F PROTEIN DNA VACCINE DRIVES A TH1 POLARIZED AND ENHANCED PROTECTIVE IMMUNE RESPONSE

A Built-In CpG Adjuvant in RSV F Protein DNA Vaccine Drives a Th1 Polarized and Enhanced Protective Immune Response

Human respiratory syncytial virus (RSV) is the most significant cause of acute lower respiratory infection in children.However, there is no licensed vaccine available.Here, we investigated the effect of five or 20 copies of C-Class of CpG ODN (CpG-C) motif incorporated into a plasmid DNA vaccine encoding RSV fusion (F) glycoprotein on the vaccine-i

read more

Genome-Wide Association Study Identifies Genomic Loci Associated With Neurotransmitter Concentration in Cattle

Abnormal neurotransmitter concentration is one of the factors that affect the health status, behavioral personality, and welfare level of animals, but the genetic basis of the abnormality is still largely unknown.The objective of this study is to identify putative genomic loci associated with neurotransmitter concentration in cattle.We measured ser

read more

Mechanical properties and microstructural characteristics of rotary friction welded dissimilar joints of rolled homogeneous armor steel and medium carbon steel

Distinct materials are used for the construction of battle tanks used in defense sectors.The hull and turret of the battle tanks are made up of rolled homogeneous armor steel (also known as armor steel).The inner portions like the driver cabin and control room are covered with medium carbon steel.Hence, the dissimilar joint between these materials

read more